Hypertension

HYPERTENSION: It is defined as a consistent constant elevation of the systolic or diastolic pressure above 140/90mm Hg. It is sustained deviation of blood pressure.

Hypertensive Drugs:

1.      Diuretics

·         Thiazides , Metalazine, chlorothiazide, lasix, bumetanide

2.      Adrenergic (sympathetic) inhibitors

·         Aldomat, cloridine, gunabenz, serpentine, timolol

3.      Vasodilators

·         Diazoxide, hydralazine, minoxidil, nitroglycerine

4.      Angiotension inhibitors

·         Benazeprol, captopril, clazapril, moexpril, perindopril

5.      Calcium channel blockers

Amlodipine, diltiazen, felodipine, verapanil, mibefradil

Adverse effects of Hypertensive drugs

·         Fluid electrolyte imbalances: hypocalaemia, hypercalcaemia, metabolic alkalosis

·         CNS effects: Headache, weakness, vertigo, dizziness, restlessness, depression 

·         GI effects: Anorexia, nausea vomiting, diarrhea , constipation, dry mouth

·         Photosensitivity and skin rash

·         Metabolic effects: hypeuricaemia, hyperglycaemia, increased LDL cholesterol